有关MXE使用的了解

MXE的名称代表甲氧胺，或其全名，2-（3-甲氧基苯基）-2-（乙基氨基）环己酮。MXE是来自芳基环己基胺类化合物的药物。芳基环己基胺还包括ketamineandPCP这是两年后的两种药物，已经用于人类和动物的麻醉。

相比之下，MXE是最近开发的物质，已经专门开发并用作娱乐药物。MXE与氯胺酮不同的分子水平不同。初始报告表明，尽管其半法地位，MXE具有比氯胺酮更持久和更强烈的效果。

没有任何正式的研究可以逐步展示MXE的工作原理，但假设通过影响大脑的氯胺酮的方式相同的方式工作neurotransmittersand acting on their receptors. In addition to glutamate and aspartate one of the neurotransmitters thought to be affected is dopamine, which is associated with feelings of euphoria, and has a role in many addictions, includingsubstance use disorders。

Given the fact that it has only emerged as a recreational drug in the last decade, very little is known about how to manage the medical consequences of the drug, making it a risky substance to take.

Also Known As:甲氧胺也被称为MXE，M-KET（有时写入M KET），K MAX，K-MAXX，KMAXX），MEXXY（有时写为MEXY，MEXXI），MEXXIEM，MKAT，MXXE，甲氧酰胺，甲氧嘧嘧啶和甲氧肟。

Drug Class:MXE is an芳基环己胺。它被归类为一个分离的幻影原。

Common Side Effects:MXE可能导致increased energy, euphoria, auditory and visual hallucinations, disassociation (m-hole), severe ataxia, nystagmus

mxe做了什么？

有几种方式占据了mxe。有些人口服或舌下（舌下）。有些人通过鼻吹塑或snortingit into the nose. It can also be inserted into the rectum, where it's absorbed into the bloodstream, orinjectedinto a muscle.

Doses typically range from 5 mg to 90 mg. If the drug is snorted, it can take 30 to 90 minutes to feel the effect, which can cause users to "top-up" or take more before the drug kicks in. This is a dangerous practice because the drug can build up in your system and lead to synergistic adverse effects. The effects usually last for one to three hours. If MXE is injected, the effects can begin within five minutes and last for as little as one hour.

Like other精神毒品, the MXE high is described as pleasurable and includes stimulant, relaxant, and dissociative effects. But MXE also has unpredictable and intense side effects—particularly with higher doses—that are extremely unpleasant both physically and psychologically.

What the Experts Say

MXE has been available on the Internet since 2010 through online chemical manufacturers and head shops who sell it as a "research chemical" and as a "legal high." By being marketed as a research chemical, which is a way that designer drugs can be sold semi-legally, it can potentially get through a legal loophole.

The lack of credible research evidence on MXE makes it a risky substance to take both in the short term and the long term. In the short term, if you suffer from acute complications of the drug, the doctors who try to help you in the emergency room will likely not be well-versed in what you have taken or how to best treat it.

Information is not yet available on the long-term effects of MXE, so we don't currently know how taking MXE might affect your future mental or physical health, your fertility, or the health of your baby if you are pregnant or breastfeeding when you take it.

Common Side Effects

MXE has stimulant and dissociative effects, with the stimulant effects predominating at lower doses and the dissociative effects at higher doses. Depending on the set and setting and your personal reaction to the drug, you can experience an altered state of consciousness that can range from a dreamlike state to a terrifyingbad tripexperience of heightened, intense anxiety that can go on for several hours.

Lower Doses (up to 20 mg):
These feelings can continue as an "afterglow" for one to two hours after the main effects of the drug wear off.

• Feeling of calmness
• Increased energy
• Euphoria
• 断开问题和担忧

Higher doses (40 mg to 50 mg):
When taken in higher doses, the effects of MXE are much more intense (and more similar to related drugs like ketamine and PCP), including:

• Feelings of intense醉酒
• 焦虑
• 听觉和视觉幻觉
• Feeling disconnection from your body
• 严重的共济失调（缺乏协调和笨拙）
• 眼球震颤（一种导致非自愿摇晃或摇晃眼睛的条件）
• Dissociation（通常被称为平行的“m孔”k-holeexperience on ketamine)

Hospital reports show that, while people can recover from MXE toxicity, this recovery period can require several days of hospitalization, with treatment including detox medication, intravenous fluids, and respiratory support. In addition, news stories have blamed several deaths on the consumption of the drug.

Very little objective information is available about MXE—most of it is anecdotal, posted on internet forums by users, or reported by emergency physicians who have dealt with acute cases. These individual reports give an idea of what someone says about their personal experience with the drug, but do not necessarily predict other users' experiences.

Signs of Use

如果您关心的人使用MXE，您可能会注意到以下标志：

• 睡眠习惯的变化
• Shifts in priorities
• Sudden change in social network
• Irritability
• Mood changes
• 药物用具的存在

Myths & Common Questions

New psychoactive substances or "legal highs" like MXE are not a safe, legal alternative to ketamine—in fact, they are often more potent and unpredictable than the illicit drug they are designed to mimic.

Tolerance, Dependence, and Withdrawal

来自用户的轶事报告表明耐受性快速地建立起来，药物具有很大的成瘾潜力。一些用户报告每天服用高剂量，以努力保持对初始低剂量的积极影响。这通常与情绪困难和相关的社会问题相结合。有关MXE依赖的数据有限，但研究人员认为，它与氯胺酮的相似性可能意味着它具有类似的依赖风险。

How Long Does MXE Stay in Your System?

The length of time MXE stays in your system depends on several factors, including how much you take and how you take it (i.e., orally, snorted, or injected) as well as your age, metabolism, hydration, and activity levels. MXE is not detected via a standard urine toxicology screen.

Addiction

Addiction to MXE is certainly possible, especially since it is thought to affect the neurotransmitter dopamine, which signals the brain that a reward is on its way. When users experience a spike in dopamine levels, it reinforces the desire to use again and the brain requires more and more of the drug to achieve feelings of pleasure. The result: compulsive drug-seeking behavior. This can include spending large amounts of time seeking and using the drug and neglecting work and family responsibilities.

由于有很少的信息，许多成瘾辅导员和医务人员可能甚至没有听说过这种药物，更不用说了解这一效果。这可以使形成治疗性关系和有效的成瘾治疗该药物特别具有挑战性。

撤军

Once people have developed a dependence on or addiction to MXE, they are likely to experience symptoms of withdrawal if they suddenly stop taking the drug. These symptoms can range from mild to serious and can impact the body and mind, including:

• 抑郁思想
• Insomnia
• Memory loss
• Impaired judgment
• Disorientation
• Clumsiness
• Body aches and pains

如何获得帮助

While there is no specific treatment for MXE addiction, there are some proven treatment options that could help you or someone you love. Treatment may include supervised detox, rehab (inpatient, outpatient, or residential),cognitive-behavioral therapy,family therapy, support groups, relapse prevention, and medication for any共同发生精神疾病。

如果您使用MXE使用问题，请与您的医生交谈。在一起，您可以弄清楚正确的待遇，以开始持续恢复。